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A Transplantable Nephroblastoma (Wilms' Tumor) and Other Spontaneous Tumors in a Colony of Rats

(From the Department of Pathology, The New York Hospital, Cornell Medical Center, New York, N.Y.)

A spontaneous nephroblastoma with sarcomatous and tubular elements arose adjacent to the remaining kidney of a rat from which one kidney had been removed. The tumor was transplanted to a second, and retransplanted to a third, closely related rat. In both cases, the cells of the transmitted tumor were uniformly sarcomatous. The tumor could not be transplanted to unrelated rats. Nine other spontaneous tumors are cited.

Received 5/16/50.