This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Galinsky, I. Search for Related Content PubMed PubMed Citation Articles by Galinsky, I.

The Uptake and Distribution of Radioactive Phosphorus in Chicken Eggs Containing a Rapidly Growing Mammary Tumor of a C3H Mouse^*

(From Baylor Medical College, Houston, Texas)

1. A C3H mammary carcinoma was grown in fertile chicken eggs by the yolk sac injection technic.

2. Radioactive phosphorus in a 1 per cent Na₂HPO₄ solution was injected between the chorio-allantoic membrane and the egg shell 8 days after tumor inoculation.

3. The P³² was taken up by the blood stream and distributed throughout the egg. At 48 hours most of the P³² was found in the allantoic fluid. The tumor took up more P³² than either the chick embryo brain or liver. The chick embryo skeleton accumulated P³² more rapidly than the mouse tumor and at 96 hours after injection contained about 5 times as much.

^* This work was done at the University of Texas under a Rosalie B. Hite Cancer Fellowship.

Received 6/ 7/50.