This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Hirschberg, E. Articles by Rusch, H. P. Search for Related Content PubMed PubMed Citation Articles by Hirschberg, E. Articles by Rusch, H. P.

Comments on Recent Experiments with Frozen and Dried Tissue as Evidence for the Virus Etiology of Tumors

(From the McArdle Memorial Laboratory, Medical School, University of Wisconsin, Madison 6, Wisconsin)

The data on the propagation of mammalian tumors in the absence of intact cells obtained by Gye et al. with freezing and drying technics are summarized and discussed. It is pointed out that a fair amount of evidence exists for the survival of normal cells after freezing. The occasional growth of tumor tissue in tissue culture after freezing further indicates that freezing technics alone are not suitable for the solution of this problem. The introduction of drying after freezing appears to provide stronger evidence against the presence of intact cells. Some questions are raised which must be answered before the data obtained by freezing-drying can be completely evaluated.

^* Fellow, American Cancer Society, on recommendation of the Committee on Growth of the National Research Council.

Received 4/ 4/50.