This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Begg, R. W. Search for Related Content PubMed PubMed Citation Articles by Begg, R. W.

Systemic Effects of Tumors in Rats^*

R. W. Begg

( Cancer Research Laboratory, Department of Biochemistry, Dalhousie University, Halifax, N.S.)

Tumor-bearing rats exhibit enlargement of the adrenal with loss of ascorbic acid and cholesterol, atrophy of the thymus, diminution in liver catalase activity, and progressive anemia.

The thesis that rats bearing large tumors are in a state of hypofunction of the adrenal cortex requires further substantiation, and in any event such a state would not explain the observed systemic effects.

^* Aided by grants from the Donner Foundation, the National Cancer Institute of Canada, and the Nova Scotia Division of the Canadian Cancer Society.

Research Associate, National Cancer Institute of Canada. Present address: Department of Medical Research, University of Western Ontario, London, Canada.

Received 12/ 6/50.

This article has been cited by other articles:

				H. Rubin Cancer cachexia: Its correlations and causes PNAS, April 29, 2003; 100(9): 5384 - 5389. [Abstract] [Full Text] [PDF]