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Studies on a Tumor-retarding Agent Produced by Aspergillus fumigatus^*

( Division of Experimental Chemotherapy, The Sloan-Kettering Institute for Cancer Research, New York, N.Y.)

Preparations having the ability to inhibit the growth of Sarcoma 180 in mice have been extracted from the culture filtrate and mycelial pads of Aspergillus fumigatus. Chemical and electrophoretic data indicate that the active principle or principles may be basic proteins.

^* This work was aided by grants from the American Cancer Society and the National Cancer Institute of the Public Health Service.

Received 1/ 5/51.