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The Effect of Visible Light on the Development in Mice of Skin Tumors and Leukemia Induced by Carcinogens^*

( Division of Cancer Research, Department of Surgery and Zoölogy, The University of Rochester, Rochester, N.Y.)

Mice of the dilute brown (DBA) strain kept in an environment of visible light for 12 hours daily or in complete darkness were painted with solutions of 3,4-benzpyrene or 20-methylcholanthrene. The incidence of leukemia among the mice exposed to light was significantly higher than in those kept in the dark. Fewer animals exposed to light developed skin carcinomas.

^* Aided by a grant from the Rockefeller Foundation and the Jane Coffin Childs Memorial Fund for Medical Research.

Received 4/ 7/51.