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Serum Tributyrinase Levels in Mice of the C57, C3H, and A Strains^*

( Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada)

1. Serum tributyrinase levels have been determined for mice of the C3H, A, and C57 strains.

2. Statistically significant effects on enzyme activity are associated with age, sex, previous pregnancy, and strain.

3. There is no evidence that the serum tributyrinase activity is related to susceptibility or resistance to cancer.

^* The mice for these investigations were made available through the kindness of Dr. H. E. Rawlinson, Department of Anatomy, University of Alberta.

The investigation was supported by a grant from the National Cancer Institute of Canada.

Received 10/ 1/51.