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Effect of Irradiation on the Universal Reaction in Cancer^*

( Serology Laboratory and Department of Roentgenology, University Hospital, University of Michigan, Ann Arbor, Mich.)

Preliminary studies of universal reactions before and after irradiation of cancer patients led to the following results:

1. Patients whose universal reactions exhibited a rise in precipitation following irradiation were found to manifest clinically a normal post-irradiation course.

2. Patients whose universal reactions exhibited no rise or a decline in precipitation following irradiation were found to be in a very poor state clinically and did not manifest a normal post-irradiation course.

^* This work has been supported by the Atomic Energy Commission, under Contract No. AT (11-1)-33. Principal investigators: Reuben L. Kahn and Fred J. Hodges, University Hospital, University of Michigan, Ann Arbor, Mich.

Received 8/13/51.