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( Department of Radiology, Stanford University School of Medicine, San Francisco 15, Calif.)
In two experiments concerned with radiation-induced lymphoid tumors of C57 black mice, it has been shown that: (a) testosterone inhibits lymphoma development only when given concurrently with irradiation and (b) the inhibitory effect of testosterone previously noted in male mice of this strain is also observed in females, the degree of inhibition being apparently somewhat greater in spayed than in intact animals.
* This investigation was supported by a grant from the National Cancer Institute, National Institutes of Health, Public Health Service.
Received 2/24/52.
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