This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Tannenbaum, A. Articles by Silverstone, H. Search for Related Content PubMed PubMed Citation Articles by Tannenbaum, A. Articles by Silverstone, H.

The Genesis and Growth of Tumors

VI. Effects of Varying the Level of Minerals in the Diet^*

( Department of Cancer Research, Medical Research Institute, Michael Reese Hospital, Chicago 16, Ill.)

The influence of varying the salt content of the diet on the genesis and growth of the spontaneous mammary carcinoma and carcinogen-induced skin tumors of the mouse was investigated. The studies utilized partially purified rations containing a standard salt mixture at levels of 2, 4, or 8 per cent of the diet—considered to be the physiological range for dietary minerals. When the experimental conditions were controlled so that the groups of mice were equivalent as to mean caloric intake and body weight, no significant differences were observed in the incidences or mean times of appearance of the neoplasms, or in their rate of growth.

^* This investigation was supported, in part, by research grant C248 from the National Cancer Institute of the National Institutes of Health, Public Health Service.

Supported, in part, by the Michael Reese Research Foundation and the Foundation for Cancer Research, Chicago.

Received 2/16/53.

This article has been cited by other articles:

				M. R. Forman Changes in Dietary Fat and Fiber and Serum Hormone Concentrations: Nutritional Strategies for Breast Cancer Prevention over the Life Course J. Nutr., January 1, 2007; 137(1): 170S - 174S. [Abstract] [Full Text] [PDF]