This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Asboe-Hansen, G. Search for Related Content PubMed PubMed Citation Articles by Asboe-Hansen, G.

Autoradiography of Mast Cells in Experimental Skin Tumors of Mice Injected with Radioactive Sulfur (S³⁵)^*

( Laboratory for Connective Tissue Research, University Institute of Medical Anatomy, Copenhagen, Denmark)

Previous histochemical and chemical studies indicated that the granules of the connective tissue mast cells contain a sulfuric mucopolysaccharide. This substance is closely related to heparin and hyaluronic acid without being identical with either.

Stripping-film autoradiography of connective tissue in experimental skin tumors in mice injected intraperitoneally with S³⁵, with sodium sulfate as carrier, showed that the majority of the mast cells take up sulfur. This uptake manifests itself as a blackening of a stripping film.

^* This investigation was aided by grants from Eli Lilly & Co., Indianapolis, Indiana, U.S.A., the National Danish Association against Rheumatic Diseases, the Danish Anti-Cancer League, the Reinholdt W. Jorck Fund, and Merchant in Odense Johann and Hanne Weimann (née Seedorff) Fund.

Received 3/18/53.