This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Greene, H. S. N. Search for Related Content PubMed PubMed Citation Articles by Greene, H. S. N.

The Induction of the Shope Papilloma in Homologous Transplants of Embryonic Rat Skin^*

( Department of Pathology, Yale University School of Medicine, New Haven, Conn.)

Although the adult rat is resistant to the Shope papilloma virus, embryonic rat skin is susceptible. Fragments of embryonic rat skin infected with the virus and transplanted to the brains of adult animals react with typical papilloma formation. On the other hand, the refractoriness of the adult guinea pig, hamster, and mouse is shared by their embryonic tissues.

^* This investigation was supported in part by grants from the American Cancer Society upon recommendation by the Committee on Growth of the National Research Council; the Medical Research and Development Board, Office of the Surgeon General, Department of the Army, under Contract No. Da-49-007md-30; the National Cancer Institute, National Institutes of Health, Public Health Service; and the Jane Coffin Childs Memorial Fund for Medical Research.

Received 5/13/53.