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Transplantation of a Thyroid Carcinoma within the Canine Species^*

( School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pa.)

By the use of total-body irradiation followed by cortisone or hydrocortisone, a thyroid carcinoma spontaneously occurring in a Boxer dog has been transplanted with a high degree of success through seven generations of mixed-breed puppies and is now in its eighth passage. Lymph node metastases have been observed.

^* This investigation is supported by a grant from the National Cancer Institute of the U.S. Public Health Service.

Received 5/27/54.