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Experimental Production of Metaplasia in the Human Apocrine Sweat Gland^*

( Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pa.)

Proliferative squamous metaplasia of the secretory cells of the human apocrine sweat gland has been experimentally induced by inciting a low-grade local inflammatory change in the axillary skin. The metaplasia is interpreted as a process of cellular de-differentiation occurring during the regenerative and reparative process.

^* This study was supported by U.S. Public Health Service Grant No. G-3552.

Received 5/18/55.