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A Transplantable Induced Melanotic Tumor of the Syrian Golden Hamster^*

( Division of Oncology, The Chicago Medical School, and Department of Pathology, Mount Sinai Hospital, Chicago, Ill.)

Melanotic tumors induced in Syrian golden hamsters by means of 9,10-dimethyl-1,2-benzanthracene applied directly to the skin were successfully transplanted to homologous animals. The transplants resembled the originally induced lesions but showed a more pronounced and more irregular cellular proliferation. After transplantation, the tumor cells retained their ability to produce large amounts of both melanin and fibrillar reticulum.

^* This investigation was supported by a Cancer Control Grant (CS-9212) from the National Institutes of Health, U.S. Public Health Service.

Received 7/ 9/56.