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Benign and Invasive Tumors Induced in Drosophila by an Inherited Tumor-inducing Factor^*

( Division of Biology, California Institute of Technology, Pasadena, Calif.)

Crude preparations of a tumor-inducing factor obtained from tu-e larvae induce benign, free-floating tumors. The invasive tumors induced by the tumor-inducing factor in purified preparations appear to be lethal.

A new culture medium has been devised in which Drosophila tumors can be cultured successfully with and without the presence of normal tissue.

^* This work was supported by fellowships CF 5154 and CF 5155 from the National Institutes of Health, U.S. Public Health Service.

Received 7/19/56.