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Permanently Transplantable Human Tumors Maintained in Conditioned Heterologous Hosts: H. Chon. #1, H. Ep. #4, and H. Ad. #1^*

( Sloan-Kettering Institute for Cancer Research, New York 21, N.Y.)

Three additional human tumors, permanently transplantable in conditioned heterologous hosts, are described. They have all been maintained for a considerable period of time and are harvested in consistently large volumes suitable for pharmaceutical testing. The morphology of the three is diverse. H. Chon. #1 is a chondrosarcoma; H. Ep. #4 a squamous-cell carcinoma; and H. Ad. #1 an adenocarcinoma of the colon.

^* This investigation has been aided by a grant from The National Cancer Institute of the U.S. Public Health Service, Expansion of Cancer Chemotherapy, Transplantation of Human Tumors in Animals, and the Damon Runyon Memorial Fund for Cancer Research.

Received 1/26/57.