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The Lack of Effect of Heparin on Mitosis in Strain L Cells^*

( Department of Pathology, Yale University School of Medicine, New Haven, Conn.)

Strain L cells grown in suspension cultures containing 0.0001–0.1 per cent heparin showed no inhibition of mitosis or cell growth. Heparin was found intracellularly in strain L cells and was degraded by these cells.

^* This investigation was supported by research grants from the United States Public Health Service C2928 and the Stamford United Fund 56–105.

Received 8/31/57.