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Growth, Morphology, and Karyotype in Two Pairs of Human Cell Strains of Malignant and Benign Origin from the Same Individuals^*

( Department I of Pathology, University of Gothenburg, Sweden)

Two pairs of isologous human cell strains established from excised benign and malignant tissues from two individuals and cultivated synchronously have been studied with respect to growth, morphology, and karyotype. After cultivation for 2 years the four strains no longer exhibited any significant deviations in these properties. The adaptation to the in vitro milieu is discussed.

^* Supported by a grant from the Swedish Cancer Society.

Received 5/29/61.