This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Hilf, R. Articles by Borman, A. Search for Related Content PubMed PubMed Citation Articles by Hilf, R. Articles by Borman, A.

The Effect of Progressive Sarcoma 180 Growth upon the Uterotrophic Response to Estrogen in Mice^*

( Squibb Institute for Medical Research, New Brunswick, N.J.)

The uterotrophic responses to various doses of estradiol benzoate, estrone, and estriol were investigated in ovariectomized Sarcoma 180-bearing mice at different stages of tumor growth. The data indicate that the uterine response was decreased as tumor growth progressed when compared with that of the tumor-free ovariectomized control animals. Restricting food intake by pair-feeding did not alter the uterine response to estradiol benzoate in the tumor-free animals but did diminish the estrogeninduced uterine growth in tumor-bearing animals.

^* This work was supported by Contract No. Sa-43-ph-2395 from the Cancer Chemotherapy National Service Center, National Cancer Institute, National Institutes of Health.

Received 10/12/62.