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Serum Protein-bound Fucose in Patients with Breast Masses¹

Department of Surgery and Surgical-Medical Research Institute, University of Alberta, Edmonton, Canada

Serum protein-bound fucose has been determined in the total serum and the seromucoid fraction of 89 female patients presenting with a breast mass. The diagnosis of the breast lesion was subsequently established in all patients by histologic study. No significant difference exists between the levels recorded in patients bearing malignant and those in patients with benign lesions. Therefore, the previous suggestion that serum protein-bound fucose might be a useful screening procedure for patients with breast masses has not been confirmed.

¹ This investigation was supported by a grant from the National Cancer Institute of Canada (NCI No. 226) and the Vessie Heckbert Memorial Cancer Fund.

² Vessie Heckbert Summer Student.

Received 3/31/65.