This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Klein, E. Articles by Klein, G. Search for Related Content PubMed PubMed Citation Articles by Klein, E. Articles by Klein, G.

Antibody Response and Leukemia Development in Mice Inoculated Neonatally with the Moloney Virus¹

( Institute for Tumor Biology, Karolinska Institutet Medical School, Stockholm, Sweden)

Mice infected neonatally with homogenates from lymphomas induced by the Moloney virus showed a deficient or delayed antibody response, measured by the indirect fluorescent antibody test against Moloney lymphoma target cells in comparison with mice infected as adults. In neonatally infected mice there was a correlation between the development of antibodies and the length of the preleukemic latency period.

¹ This work was supported by research grants from the Damon Runyon Memorial Fund (DRG-598), the Jane Coffin Childs Memorial Fund for Medical Research, the Swedish Cancer Society, and Knut and Alice Wallenberg's Foundation.

Received 12/29/64.