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Control and Prevention of Hemorrhage: Platelet Separation¹

Children's Cancer Research Foundation and the Department of Pathology, Harvard Medical School at The Children's Hospital, Boston, Massachusetts

The development of methods for the separation and concentration of human platelets permitted their administration in sufficient quantities to control bleeding in thrombocytopenia.

Methods for separation and concentration of human platelets, by which platelet preparations can be provided as by-products of routine blood banking, have been described.

Platelet transfusions are safe and effective in the control of thrombocytopenic bleeding.

¹ This investigation was supported by research contract NYO-1753-1 from the Atomic Energy Commission, by grant FR-05219-01 from the Division of Research Facilities and Resources, by Public Health Service research grant C-6516, and by contract PH-43-64-488 from the National Cancer Institute.

² Present address: Roswell Park Memorial Institute, Buffalo, N. Y.

³ Present address: Children's Hospital of Philadelphia, Philadelphia, Pa.