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Future Possibilities for the Development of Treatments of Leukemia¹

Chester Beatty Research Institute, Institute of Cancer Research: Royal Cancer Hospital, London

To assess future possibilities of treatments of leukemia, biochemical and biologic characterizations of the disease under discussion have been reviewed. These characterizations have been used as base lines for speculations and have been summarized in Table 1. A distinction has been made between drugs that destroy leukemic cells and homeostatic regulators that might achieve palliation or cure by redressing imbalances in the leukopoietic systems.

¹ This work has been supported by grants to the Chester Beatty Research Institute (Institute of Cancer Research: Royal Cancer Hospital) from the British Empire Cancer Campaign, the Medical Research Council, and the National Cancer Institute, NIH, USPHS.