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Screening Data from the Cancer Chemotherapy National Service Center Screening Laboratories. XXVIII.

National Cancer Institute National Institutes of Health Bethesda, Maryland 20014

Data are reported on 1, 255 synthetic compounds which were tested in the CCNSC primary screens. Almost all of the compounds were tested in Sarcoma 180, Carcinoma 755, Leukemia 1210, and KB cells in culture; some tests were also carried out in Dunning leukemia ascites, Friend virus leukemia, Lewis lung carcinoma, Human sarcoma HS1, Hepatoma 129, Walker 256 (intramuscular) and Cloudman melanoma (S91). Data are reported only on compounds which have not demonstrated sufficient activity in these systems to warrant further investigation.

¹ Former Chief, Cancer Chemotherapy National Service Center.

² Biologist, Screening Section, Drug Evaluation Branch, Cancer Chemotherapy National Service Center.

³ Chief, Cancer Chemotherapy National Service Center.