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Prophylactic Treatment of Adjacent Areas in Hodgkin's Disease

Ontario Cancer Institute incorporating Princess Margaret Hospital, Toronto, Canada

The pattern of spread in Hodgkin's disease can be anticipated whenever the patient presents with regionally localized involvement. In such instances the inclusion of all immediate routes of lymphatic spread in the field of radiation directed to the involvement offers the patient many advantages.

The details involved in adequate prophylactic treatment are discussed. The primary importance of a satisfactory tumor dose level is recognized, but it becomes apparent that some degree of complementary treatment is necessary to insure successful treatment of the presenting region of involvement in Hodgkin's disease.

This review also revealed the clinical features on presentation which help to identify 2 distinct types of early Hodgkin's disease; 1 type suggesting early unifocal disease and the other type early multifocal disease.