This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Schepartz, S. A. Articles by Leiter, J. Search for Related Content PubMed PubMed Citation Articles by Schepartz, S. A. Articles by Leiter, J.

Screening Data from the Cancer Chemotherapy National Service Center Screening Laboratories. XXXV

Data are reported on 1476 synthetic compounds which were tested in the CCNSC primary screens. Almost all of the compounds were tested in Sarcoma 180, Adenocarcinoma 755, Leukemia 1210, and KB cells in culture; some tests were also carried out in Friend virus leukemia, Lewis lung carcinoma, human sarcoma HS1, Hepatoma 129, Walker 256 (intramuscular), Walker 256 (subcutaneous), and Cloudman melanoma (S91). Data are reported only on compounds which have not demonstrated sufficient activity in these systems to warrant further investigation. The number of test systems in the screening program has recently been reduced; the reasons for the reduction are discussed.

¹ Chief, Cancer Chemotherapy National Service Center, National Cancer Institute, USPHS, Bethesda, Maryland. 20014

² Biologist, Screening Section, Drug Evaluation Branch, Cancer Chemotherapy National Service Center, National Cancer Institute, USPHS, Bethesda, Maryland.

³ National Library of Medicine, USPHS, Bethesda, Maryland.