This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Williamson, C. E. Articles by Witten, B. Search for Related Content PubMed PubMed Citation Articles by Williamson, C. E. Articles by Witten, B.

Reaction Mechanism of Some Aromatic Nitrogen Mustards¹

Research Laboratories, Edgewood Arsenal, Maryland

In vitro studies of some aromatic nitrogen mustards have indicated that these cancer chemotherapeutic agents do not react through a carbonium ion as reported. Rather, they react via a 2-step process with the formation of a relatively stable intermediate similar to that described for the aliphatic nitrogen mustards.

¹ Supported by the U. S. Army Edgewood Arsenal Chemical Research and Development Laboratories In-House Laboratory Independent Research Program.

Received 4/26/66. Accepted 7/18/66.

This article has been cited by other articles:

				Z. Szilágyi and C. Fenselau Molecular Dynamics Simulation of Metallothionein-Drug Complexes Drug Metab. Dispos., February 1, 2000; 28(2): 174 - 179. [Abstract] [Full Text]