This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Robl, M. G. Articles by Olson, C. Search for Related Content PubMed PubMed Citation Articles by Robl, M. G. Articles by Olson, C.

Oncogenic Action of Bovine Papilloma Virus in Hamsters¹

Department of Veterinary Science, University of Wisconsin, Madison, Wisconsin 53706

Different isolates of bovine papilloma virus (BPV) originating from different cases induced well-differentiated subcutaneous fibrosarcomas in 67 to 100% of inoculated hamsters after an induction period ranging from 25 to 56 weeks. Age at time of inoculation had little if any effect upon the incidence or subsequent development of the BPV-induced tumors. Disseminated tumor nodules occurred in about 10% of the animals. Several tumors were transplanted to other hamsters. A review of reports on other viruses oncogenic for the hamster revealed that the incidence of tumors decreased when older animals were inoculated.

¹ Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. Supported in part with the aid of RG-C4627 and USPHS Training Grant 817, NIH.

Received 12/ 4/67. Accepted 4/15/68.

This article has been cited by other articles:

				M. Y. Gulbahar, H. Yuksel, and L. Aslan Angiokeratomatous Papilloma Associated with Papillomavirus in a Calf Vet. Pathol., September 1, 2003; 40(5): 582 - 586. [Abstract] [Full Text] [PDF]

				G. Chambers, V. A. Ellsmore, P. M. O'Brien, S. W. J. Reid, S. Love, M. S. Campo, and L. Nasir Association of bovine papillomavirus with the equine sarcoid J. Gen. Virol., May 1, 2003; 84(5): 1055 - 1062. [Abstract] [Full Text] [PDF]