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Serum and Tissue Calcium in Human Breast Carcinoma

The Harrison Department of Surgical Research, University of Pennsylvania School of Medicine and the William Pepper Laboratory, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104

Calcium determinations with atomic absorption spectrophotometry were performed on serum and on malignant tissues obtained from patients with carcinoma of the breast. No correlation was noted between either serum calcium levels or tissue calcium levels and the number of positive axillary lymph nodes. The tumor calcium content was greater than that of the control tissue. This latter finding is in conflict with some earlier reports concerning tissue calcium content.

¹ Clinical Fellow, American Cancer Society.

² Advanced Clinical Fellow, American Cancer Society.

Received 5/13/69. Accepted 7/29/69.