This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Sato, S. Articles by Ishida, Y. Search for Related Content PubMed PubMed Citation Articles by Sato, S. Articles by Ishida, Y.

Aldolase C in Experimental Brain Tumor¹

Biochemistry Division, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Tokyo, Japan [S. S., T. S.], and Department of Pathology, School of Medicine, Gunma University, Maebashi, Japan [S. K., Y. I.]

Aldolase C was detected together with aldolase A and their hybrids in a transplantable murine brain tumor, the primary tumor of which was diagnosed as glioblastoma. The pattern of aldolase in this tumor was very similar to that of a normal brain. The phenotype of aldolase isozyme was maintained, although its histological appearance was hard to diagnose as glioblastoma after successive transplantations. The usefulness of such an aldolase study in the identification of cells is emphasized.

¹ This work was supported in part by grants from Ministry of Education and Ministry of Health, Japan.

Received 7/15/69. Accepted 9/18/69.