This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Rosenberg, B. Articles by VanCamp, L. Search for Related Content PubMed PubMed Citation Articles by Rosenberg, B. Articles by VanCamp, L.

The Successful Regression of Large Solid Sarcoma 180 Tumors by Platinum Compounds¹

Biophysics Department, Michigan State University, East Lansing, Michigan 48823

The platinum compounds, cis-platinum (IV) diamminotetrachloride, and cis-platinum (II) diamminodichloride, have been reported to be active in inhibiting and regressing small solid Sarcoma 180 tumors and Leukemia L1210 tumors in mice. They were also active in successfully regressing large (Day 8) solid Sarcoma 180 tumors in 63 to 100% of the animals, with no apparent irreversible damage to the host, in a number of dose schedules.

¹ This work was supported by Research Grant GM-10890 of the National Institute of General Medical Science and Research Grant CA-11349 of the National Cancer Institute.

Received 9/12/69. Accepted 2/18/70.

This article has been cited by other articles:

				T. Watanabe, M. Takano, A. Ogasawara, T. Mikami, T. Kobayashi, M. Watabe, and T. Matsumoto Anti-Candida Activity of a New Platinum Derivative Antimicrob. Agents Chemother., October 1, 2000; 44(10): 2853 - 2854. [Abstract] [Full Text]