This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Brown, E. V. Articles by Kipp, W. H. Search for Related Content PubMed PubMed Citation Articles by Brown, E. V. Articles by Kipp, W. H.

Electron Density Studies on Quinoline Analogs of N,N'-Dimethyl-p-phenylazoaniline

Department of Chemistry, University of Kentucky, Lexington, Kentucky 40506

This paper continues the study of the relationship between electron density and carcinogenic activity for compounds related to p-dimethylaminoazobenzene (Cancer Res., 29: 1341–1344, 1969) and reports on the seven p-dimethylaminophenylazoquinolines. A relationship was found between carcinogenic activity and the pK_a of the amino nitrogen in these compounds, and in this new series a relationship also was found for carcinogenic activity and the pK_a of the azo nitrogen.

Received 12/15/69. Accepted 4/ 8/70.