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Laboratory of Viral Biology, National Cancer Institute, NIH, Bethesda, Maryland 20014 [H. T. A.], and Microbiological Associates, Inc., Walkersville, Maryland 21793 [L. S. R.]
A new murine oncogenic virus has been isolated which induces solid lymphoid tumors within a short latent period. A unique feature of this disease is the lack of thymic involvement. Thymic-independent tumor induction distinguishes this virus from the other experimental murine lymphoid leukemia viruses. In addition, massive meningeal tumors, a myelocytic leukemoid reaction, and no evidence of a disseminated leukemia constitute this disease syndrome.
1 Supported in part by the Special Virus-Cancer Program, National Cancer Institute, NIH, USPHS, Contract PH 43-67-697.
2 Present address: Children's Hospital Medical Center, Department of Medicine, Boston, Mass. 02115.
Received 12/30/69. Accepted 4/22/70.
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