This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Teillet, F. Articles by Bernard, J. Search for Related Content PubMed PubMed Citation Articles by Teillet, F. Articles by Bernard, J.

A Reappraisal of Clinical and Biological Signs in Staging of Hodgkin's Disease

Groupe d'étude sur la maladie de Hodgkin, Institut de Recherches sur les Leucémies et les Maladies du Sang, Hôpital Saint-Louis, Paris 10°, France

The current Rye classifcation no longer appears fully satisfactory for staging of Hodgkin's disease. As a result of a study of clinical, radiological, and biological data taken from the records of 402 patients from 1966 to 1970, we suggest that a new classification should take into account the following factors: the site of onset of the disease which enables a distinction between teh high cervical, mediastinal, retroperitoneal, and axillary forms, which all have their specific lymphatic extent; the involvement if any of the spleen; the biological signs as well as clinical symptoms for identification of the systemic syndrome. These changes could bring about significant consequences for therapy, especially in reducing irradiation volumes and in advocating the use of chemotherapy combined with radiotherapy.

¹ Presented by.

This article has been cited by other articles:

				J. Landman-Parker, H. Pacquement, T. Leblanc, J. L. Habrand, M. J. Terrier-Lacombe, Y. Bertrand, Y. Perel, A. Robert, C. Coze, I. Thuret, et al. Localized Childhood Hodgkin’s Disease: Response-Adapted Chemotherapy With Etoposide, Bleomycin, Vinblastine, and Prednisone Before Low-Dose Radiation Therapy--Results of the French Society of Pediatric Oncology Study MDH90 J. Clin. Oncol., April 7, 2000; 18(7): 1500 - 1507. [Abstract] [Full Text] [PDF]