This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Sizaret, P. P. Articles by Princler, G. L. Search for Related Content PubMed PubMed Citation Articles by Sizaret, P. P. Articles by Princler, G. L.

Quantitation of Human -Fetoprotein by Electroimmunodiffusion

International Agency for Research on Cancer, Lyon, France [P. P. S.], and Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland 20014 [K. R. M., G. L. P.]

The association of -1-fetoprotein in the serum of patients with primary hepatocellular carcinoma provides another possible parameter for both diagnosis and evaluation of the disease process. A technique for the quantitative measurement of this protein has been devised that uses the method of electroimmunodiffusion. This technique has greater sensitivity and is faster than radial diffusion with antibody in agar. Serums from 75 patients with hepatomas were measured for -fetoprotein, and these varied from 0.35 to 4950 g/ml.

Received 5/17/71. Accepted 7/20/71.