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The Effects of MP Virus Infection in Lymphoma¹

Department of Medicine, Division of Oncology [J. H., K. B. O.], Department of Microbiology [J. E. H.], and Department of Pathology [J. N. P. D.], Albany Medical College, Albany, New York 12208, and Division of Laboratories and Research [J. E. H.], New York State Department of Health, Albany, New York 12201

Three patients with far-advanced lymphoma were treated i.v. with MP virus, a strain of lymphocytic choriomeningitis virus. Probably because of severe depletion of their immune capacity, the infection was not controlled in two of them. No evidence of antitumor effect was observed.

¹ This work was supported in part by NIH Grant 5S01 RR05649-04 and USPHS Research Grant 5-M01-RR00094 CLR.

Received 11/30/70. Accepted 3/31/71.

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