This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ballal, N. R. Articles by Busch, H. Search for Related Content PubMed PubMed Citation Articles by Ballal, N. R. Articles by Busch, H.

Two-Dimensional Gel Electrophoresis of Acid-soluble Nucleolar Proteins of Walker 256 Carcinosarcoma, Regenerating Liver, and Thioacetamide-treated Liver¹

Department of Pharmacology, Baylor College of Medicine, Houston, Texas 77025

The acid-extractable proteins of nucleoli of Walker 256 carcinosarcoma, regenerating rat liver, and thioacetamide-treated rat liver were separated into 91, 94, and 92 spots, respectively, by two-dimensional polyacrylamide gel electrophoresis. Although the protein patterns from these different nucleoli have remarkable similarities, some qualitative and quantitative differences were found among these patterns. Spots A6' and B16' were found only in Walker 256 nucleoli, whereas C11' and C16' were found in regenerating and thioacetamide-treated livers. Among these nucleoli, quantitative differences were found in spots A11, A24, B1, B2, B12, B34, C8, C11, and C17.

¹ These studies were supported by USPHS Grants GM/670 and CA-10893, P.3.

Received 6/28/73. Accepted 8/16/73.