This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Segaloff, A. Search for Related Content PubMed PubMed Citation Articles by Segaloff, A.

Inhibition by Progesterone of Radiation-Estrogen-induced Mammary Cancer in the Rat¹

Alton Ochsner Medical Foundation, New Orleans, Louisiana 70121

The data from this preliminary experiment make it appear that continuous administration of progesterone protects animals from the synergism between estrogen and radiation. However, it also appears that the progesterone has by itself a protective effect against the individual carcinogenic agents since fewer tumors occurred on the opposite side as well as on the radiated side. In this preliminary experiment none of the animals that bore just progesterone pellets and were radiated developed mammary carcinomata.

¹ This study was supported by Grant 103-70 from the Cancer Association of Greater New Orleans.

Received 12/26/72. Accepted 2/12/73.