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Regan Isoenzyme in Normal Human Sera

Ames Research Laboratory, Ames Company, Division Miles Laboratories, Inc., Elkhart, Indiana 46514 [M. U.-G., F. M. Y.], and Pathology Consultants, Inc., Michigan City, Indiana 46360 [A. F. de C.]

The Regan isoenzyme of alkaline phosphatase was demonstrated in the sera of 50 normal healthy individuals by a very sensitive immunochemical test system. Several properties of the isoenzyme isolated from a pool of the normal sera were studied and were found to be identical to those of placental alkaline phosphatase.

Received 12/ 5/73. Accepted 6/14/74.