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Alopecia Activity of Cyclophosphamide Metabolites and Related Compounds in Sheep

United States Department of Agriculture, Agricultural Research Service, Metabolism and Radiation Research Laboratory, Fargo, North Dakota 58102

Thirteen analogs of cyclophosphamide were tested for defleecing activity in sheep. Activity was found only in compounds having two chloroethyl groups and a cyclophosphamide-type ring.

Received 5/13/74. Accepted 6/27/74.