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Studies of Tumor-specific and Herpesvirus Nonvirion Antigens¹

Laboratory for Virus and Cancer Research, Department of Medicine, George Washington University School of Medicine, Washington, D. C. 20037 [A. H., L. J. S.]; Department of Oncologic Virology, Institute of Clinical Medicine, University of Naples, 80138 Naples, Italy [G. T.]; Istituto Farmacoteripco Italiano, Via Salaria 971, Rome 0199, Italy [W. A. F.]; and Department of Pathology, Columbia Hospital for Women, Washington, D. C. 20037 [W. J.]

Tumor-associated cell antigens have been identified for certain squamous carcinomas. One group of tumor antigens present on these cells is herpesvirus-induced nonvirion antigens. Another group of tumor cell antigens is also identified. Both groups of antigens produce cell-mediated immune reactions. Studies of their possible value as immunogenic and immunodiagnostic agents are indicated.

¹ Presented at the International Symposium on Human Tumors Associated with Herpesviruses, March 26 to 28, 1973, Bethesda, Md.

² Presented by.