This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Speck, W. T. Articles by Rosenkranz, H. S. Search for Related Content PubMed PubMed Citation Articles by Speck, W. T. Articles by Rosenkranz, H. S.

Mutagenicity of Azathioprine¹

Departments of Pediatrics and Microbiology , College of Physicians and Surgeons, Columbia University, New York, New York 10032

Azathioprine (6-[(1-methyl-4-nitroimidazol-5-yl)thio]purine; Imuran) is mutagenic for Salmonella typhimurium. Demonstration of this mutagenic effect requires a period of anaerobic incubation of the bacteria with the test agent.

¹ This investigation was supported by The Division of Cancer Cause and Prevention, National Cancer Institute (NO1 CP-33395) and by the National Institute of Allergy and Infectious Diseases (AI-11470).

² Vivian Allan Fellow in Clinical Medicine.

³ Research Career Development Awardee of the National Institute of General Medical Sciences (5 K3 GM29,024).

Received 7/18/75. Accepted 9/16/75.

This article has been cited by other articles:

				P. Mrass, M. Rendl, M. Mildner, F. Gruber, B. Lengauer, C. Ballaun, L. Eckhart, and E. Tschachler Retinoic Acid Increases the Expression of p53 and Proapoptotic Caspases and Sensitizes Keratinocytes to Apoptosis: A Possible Explanation for Tumor Preventive Action of Retinoids Cancer Res., September 15, 2004; 64(18): 6542 - 6548. [Abstract] [Full Text] [PDF]