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Light-induced Mutagenicity of Neutral Red (3-Amino-7-dimethylamino-2-Methylphenazine Hydrochloride)¹

Department of Microbiology, New York Medical College, Valhalla, New York 10595 [B. G., H. S. R.], and Department of Pediatrics, Columbia University, New York, New York 10032 [W. T. S.]

Illumination of Salmonella typhimurium in the presence of neutral red (3-amino-7-dimethylamino-2-methylphenazine hydrochloride) results in mutations of the base substitution type.

¹ This study was supported by Grant NO1-CP-33395 from the Division of Cancer Cause and Prevention, National Cancer Institute, and Grant AI-11470 from the National Institute of Allergy and Infectious Diseases.

² To whom requests for reprints should be addressed.

Received 9/30/76. Accepted 12/30/76.