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Effects of Cancers of the Endocrine and Central Nervous Systems on Nutritional Status¹

Clinical Center, National Institutes of Health, Bethesda, Maryland 20014

Tumors of the endocrine system and cancers exhibiting paraendocrine behavior can secrete peptides that stimulate secretions of the gastrointestinal tract. This may lead to malabsorption diarrhea and consequent weight loss. Tumors may also utilize excessive amounts of specific nutrients thereby creating deficiencies. Within the central nervous system, strategically placed tumors can cause major deviations from normal in appetite. Some of these perturbations, in lesser degree, may contribute to the weight changes frequently observed in patients with cancer.

¹ Presented at the Conference on Nutrition and Cancer Therapy, November 29 to December 1, 1976, Key Biscayne, Fla.