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Radioisotope Section Scanning¹

Department of Nuclear Medicine, Middlesex Hospital Medical School, London, United Kingdom

Radioisotope section scanning, a relatively new imaging technique, can be regarded as "in vivo autoradiography." It permits, via computer utilization, reconstruction of a three-dimensional image of the distribution of a radioactive tracer within the body. Rapid progress in the design of instrumentation has allowed for initial clinical trials to be carried out. Worldwide, some 30 centers are currently engaged in research in this field, simultaneously ascertaining the physical performance characteristics and figures of merit of the different apparatuses and clarifying the most promising areas of clinical application.

This paper is concerned only with radioisotope section scanning via standard radionuclides and radiopharmaceuticals. It does not address itself to work involving positron-emitting radionuclides. Data are given on the physical parameters and areas of clinical application of several types of available equipment.

¹ Presented at the UICC Workshop on Radioimmunodetection of Cancer, July 19 to 21, 1979, Lexington, Ky.