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Potential Pathological Application of Immunocytochemical Methods to the Detection of Micrometastases¹

Royal Marsden Hospital, Sutton, Surrey SM2 5PT [J. P. S.]; Institute of Cancer Research, The Royal Marsden Hospital, Sutton, Surrey SM2 5PX [M. G. O.] and Ludwig Institute for Cancer Research (London Branch), Sutton, Surrey SM2 5PX [A. M. N.] England

Immunocytochemical methods can be used to demonstrate tumor products and antigens at the cellular level. This approach facilitates the classification of tumors and the detection of small metastatic tumor foci in biopsy material from various sites including the bone marrow.

¹ Presented at the UICC Workshop on Radioimmunodetection of Cancer, July 19 to 21, 1979, Lexington, Ky. M.G.O. is supported by a grant from the Medical Research Council, U.K.