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General Anesthesia for Whole-Body Hyperthermia¹

Departments of Anesthesiology [L. H. C., D. L. B.] and Internal Medicine [J. M. B.], The University of Texas Medical School at Houston, Houston, Texas 77030

General anesthesia was used to facilitate 259 whole-body hyperthermia treatments in 90 patients. These patients fell into American Society of Anesthesiologists Classifications 3 (moderate to severe systemic disease) and 4 (severe systemic disease with life-threatening potential). Whole-body hyperthermia imposes severe stress on cardiopulmonary and renal function. In this series, elevation of temperature from 38° to 41.5° raised cardiac output to approximately 200% of control, while oxygen consumption rose 35%. General anesthesia provides conditions which allow for more precise control and support of vital signs, fluid requirements, and blood gases.

¹ Presented at the Workshop Conference on Hyperthermia in Cancer Treatment, March 19 to 21, 1984, Tucson, AZ.

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