Cancer Research Translational Medicine Conference in Israel
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cancer Prevention Research
Cancer Prevention Journals Portal Cancer Reviews Online
Annual Meeting Education Book Meeting Abstracts Online
[Cancer Research 47, 5616-5619, November 1, 1987]
© 1987 American Association for Cancer Research
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tokunaga, K.
Right arrow Articles by Sakiyama, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tokunaga, K.
Right arrow Articles by Sakiyama, S.

Enhanced Expression of a Glyceraldehyde-3-phosphate Dehydrogenase Gene in Human Lung Cancers1

Katsuo Tokunaga, Yohko Nakamura, Kanae Sakata2, Kumie Fujimori, Michiko Ohkubo3, Kinya Sawada and Shigeru Sakiyama

Division of Biochemistry [K. T., Y. N., Ka. S., K. F., M. O., S. S.] and Thoracic Disease [Ki. S.], Chiba Cancer Center Research Institute and Hospital, 666-2, Nitona, Chiba 280, Japan

We have shown that a Mr 37,000 protein whose expression is strongly enhanced in human lung cancer tissues is the subunit of glyceraldehyde-3-phosphate dehydrogenase (GAPDH, EC 1.2.1.12). We have isolated a GAPDH complementary DNA from human lung cancer cells and deduced the complete amino acid sequence of the encoded protein. The structure of the lung cancer GAPDH is identical to that of liver GAPDH. In addition, we have found that GAPDH mRNA expression is markedly increased in human lung cancer tissues. These results disclose a molecular basis of increased glycolysis in cancer cells and reveal an important role of energy creating reaction in cancer cell growth.

1 This project was funded by a Grant-in-Aid from the Ministry of Health and Welfare for the Comprehensive 10-Year Strategy for Cancer Control, Japan.

2 Present address: Life Science Institute, Sophia University, 7-1 Kioi, Chiyoda, Tokyo 102, Japan.

3 Present address: Kagoshima Immaculate Heart College, Kamoike, Kagoshima 890, Japan.

Received 3/13/87. Revised 6/16/87. Accepted 7/28/87.




This article has been cited by other articles:


Home page
 J. Histochem. Cytochem.Home page
A. Iwase, H. Ando, T. Nagasaka, M. Goto, T. Harata, and F. Kikkawa
Distribution of Endothelin-converting Enzyme-1 and Neutral Endopeptidase in Human Endometrium
J. Histochem. Cytochem., December 1, 2007; 55(12): 1229 - 1235.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
Z.-X. Du, H.-Q. Wang, H.-Y. Zhang, and D.-X. Gao
Involvement of Glyceraldehyde-3-Phosphate Dehydrogenase in Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Death of Thyroid Cancer Cells
Endocrinology, September 1, 2007; 148(9): 4352 - 4361.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
S.-J. Chang, T.-Y. Wang, Y.-H. Lee, and C.-J. Tai
Extracellular ATP activates nuclear translocation of ERK1/2 leading to the induction of matrix metalloproteinases expression in human endometrial stromal cells
J. Endocrinol., June 1, 2007; 193(3): 393 - 404.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. Iwase, H. Ando, T. Nagasaka, D. Shibata, T. Harata, Y. Shimomura, M. Goto, and F. Kikkawa
Neutral Endopeptidase Expressed by Decidualized Stromal Cells Suppresses Akt Phosphorylation and Deoxyribonucleic Acid Synthesis Induced by Endothelin-1 in Human Endometrium
Endocrinology, November 1, 2006; 147(11): 5153 - 5159.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
G.-J. C. M. van den Bemd, J. Krijgsveld, T. M. Luider, A. L. van Rijswijk, J. A. A. Demmers, and G. Jenster
Mass Spectrometric Identification of Human Prostate Cancer-derived Proteins in Serum of Xenograft-bearing Mice
Mol. Cell. Proteomics, October 1, 2006; 5(10): 1830 - 1839.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
J.-T. Chen, T.-S. Lin, K.-C. Chow, H.-H. Huang, S.-H. Chiou, S.-F. Chiang, H.-C. Chen, T.-L. Chuang, T.-Y. Lin, and C.-Y. Chen
Cigarette Smoking Induces Overexpression of Hepatocyte Growth Factor in Type II Pneumocytes and Lung Cancer Cells
Am. J. Respir. Cell Mol. Biol., March 1, 2006; 34(3): 264 - 273.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Dooley, H. M. Said, A. M. Gressner, J. Floege, A. En-Nia, and P. R. Mertens
Y-box Protein-1 Is the Crucial Mediator of Antifibrotic Interferon-{gamma} Effects
J. Biol. Chem., January 20, 2006; 281(3): 1784 - 1795.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
S. Spaderna, B. Kropff, Y. Kodel, S. Shen, S. Coley, S. Lu, W. Britt, and M. Mach
Deletion of gpUL132, a Structural Component of Human Cytomegalovirus, Results in Impaired Virus Replication in Fibroblasts
J. Virol., September 15, 2005; 79(18): 11837 - 11847.
[Abstract] [Full Text] [PDF]

Home page
 Endocr Relat CancerHome page
J.-H. Choi, K.-C. Choi, N. Auersperg, and P. C K Leung
Gonadotropins upregulate the epidermal growth factor receptor through activation of mitogen-activated protein kinases and phosphatidyl-inositol-3-kinase in human ovarian surface epithelial cells
Endocr. Relat. Cancer, June 1, 2005; 12(2): 407 - 421.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. M. Carroll, L. R. Haines, T. W. Pearson, P. G. Fallon, C. M. Walsh, C. M. Brennan, E. P. Breen, and R. K. Porter
Identification of a Functioning Mitochondrial Uncoupling Protein 1 in Thymus
J. Biol. Chem., April 22, 2005; 280(16): 15534 - 15543.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
Y. Nakamura, K. Igarashi, T. Suzuki, J. Kanno, T. Inoue, C. Tazawa, M. Saruta, T. Ando, N. Moriyama, T. Furukawa, et al.
E4F1, a Novel Estrogen-Responsive Gene in Possible Atheroprotection, Revealed by Microarray Analysis
Am. J. Pathol., December 1, 2004; 165(6): 2019 - 2031.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
J.-H. Choi, K.-C. Choi, N. Auersperg, and P. C. K. Leung
Overexpression of Follicle-Stimulating Hormone Receptor Activates Oncogenic Pathways in Preneoplastic Ovarian Surface Epithelial Cells
J. Clin. Endocrinol. Metab., November 1, 2004; 89(11): 5508 - 5516.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
H. Utsunomiya, K. Ito, T. Suzuki, T. Kitamura, C. Kaneko, T. Nakata, H. Niikura, K. Okamura, N. Yaegashi, and H. Sasano
Steroid Sulfatase and Estrogen Sulfotransferase in Human Endometrial Carcinoma
Clin. Cancer Res., September 1, 2004; 10(17): 5850 - 5856.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
X. Hu, S. Hipolito, R. Lynn, V. Abraham, S. Ramos, and F. Wong-Staal
Relative gene-silencing efficiencies of small interfering RNAs targeting sense and antisense transcripts from the same genetic locus
Nucleic Acids Res., August 27, 2004; 32(15): 4609 - 4617.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. P. Sundararaj, R. E. Wood, S. Ponnusamy, A. M. Salas, Z. Szulc, A. Bielawska, L. M. Obeid, Y. A. Hannun, and B. Ogretmen
Rapid Shortening of Telomere Length in Response to Ceramide Involves the Inhibition of Telomere Binding Activity of Nuclear Glyceraldehyde-3-phosphate Dehydrogenase
J. Biol. Chem., February 13, 2004; 279(7): 6152 - 6162.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
A. El-Sherbeny, H. Naggar, S. Miyauchi, M. S. Ola, D. M. Maddox, P. M. Martin, V. Ganapathy, and S. B. Smith
Osmoregulation of Taurine Transporter Function and Expression in Retinal Pigment Epithelial, Ganglion, and Muller Cells
Invest. Ophthalmol. Vis. Sci., February 1, 2004; 45(2): 694 - 701.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
K. Takahashi, C. Nishiyama, M. Hasegawa, Y. Akizawa, and C. Ra
Regulation of the Human High Affinity IgE Receptor {beta}-Chain Gene Expression Via an Intronic Element
J. Immunol., September 1, 2003; 171(5): 2478 - 2484.
[Abstract] [Full Text] [PDF]

Home page
 Innate ImmunityHome page
R. Tamai, S. Sugawara, O. Takeuchi, S. Akira, and H. Takada
Synergistic effects of lipopolysaccharide and interferon-{gamma} in inducing interleukin-8 production in human monocytic THP-1 cells is accompanied by up-regulation of CD14, Toll-like receptor 4, MD-2 and MyD88 expression
Innate Immunity, June 1, 2003; 9(3): 145 - 153.
[Abstract] [PDF]

Home page
 Cancer Res.Home page
T. Suzuki, T. Nakata, Y. Miki, C. Kaneko, T. Moriya, T. Ishida, S. Akinaga, H. Hirakawa, M. Kimura, and H. Sasano
Estrogen Sulfotransferase and Steroid Sulfatase in Human Breast Carcinoma
Cancer Res., June 1, 2003; 63(11): 2762 - 2770.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
A. Tautenhahn, B. Brune, and A. von Knethen
Activation-induced PPAR{gamma} expression sensitizes primary human T cells toward apoptosis
J. Leukoc. Biol., May 1, 2003; 73(5): 665 - 672.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
S. Khosravi and P. C. K. Leung
Differential Regulation of Gonadotropin-Releasing Hormone (GnRH)I and GnRHII Messenger Ribonucleic Acid by Gonadal Steroids in Human Granulosa Luteal Cells
J. Clin. Endocrinol. Metab., February 1, 2003; 88(2): 663 - 672.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
C.-S. Chou, C.-J. Tai, C. D. MacCalman, and P. C. K. Leung
Dose-Dependent Effects of Gonadotropin Releasing Hormone on Matrix Metalloproteinase (MMP)-2, and MMP-9 and Tissue Specific Inhibitor of Metalloproteinases-1 Messenger Ribonucleic Acid Levels in Human Decidual Stromal Cells in Vitro
J. Clin. Endocrinol. Metab., February 1, 2003; 88(2): 680 - 688.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. A. Davies, W. Wang, T. G. Hales, and E. F. Kirkness
A Novel Class of Ligand-gated Ion Channel Is Activated by Zn2+
J. Biol. Chem., January 3, 2003; 278(2): 712 - 717.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Microbiol.Home page
N. Konomi, E. Lebwohl, K. Mowbray, I. Tattersall, and D. Zhang
Detection of Mycobacterial DNA in Andean Mummies
J. Clin. Microbiol., December 1, 2002; 40(12): 4738 - 4740.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
C.-S. Chou, H. Zhu, E. Shalev, C. D. MacCalman, and P. C. K. Leung
The Effects of Gonadotropin-Releasing Hormone (GnRH) I and GnRH II on the Urokinase-Type Plasminogen Activator/Plasminogen Activator Inhibitor System in Human Extravillous Cytotrophoblasts in Vitro
J. Clin. Endocrinol. Metab., December 1, 2002; 87(12): 5594 - 5603.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
Y. Miki, T. Nakata, T. Suzuki, A. D. Darnel, T. Moriya, C. Kaneko, K. Hidaka, Y. Shiotsu, H. Kusaka, and H. Sasano
Systemic Distribution of Steroid Sulfatase and Estrogen Sulfotransferase in Human Adult and Fetal Tissues
J. Clin. Endocrinol. Metab., December 1, 2002; 87(12): 5760 - 5768.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
T. Maisch, B. Kropff, C. Sinzger, and M. Mach
Upregulation of CD40 Expression on Endothelial Cells Infected with Human Cytomegalovirus
J. Virol., November 13, 2002; 76(24): 12803 - 12812.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. Zhang, R. C. M. Simmen, F. J. Michel, G. Zhao, D. Vale-Cruz, and F. A. Simmen
Secretory Leukocyte Protease Inhibitor Mediates Proliferation of Human Endometrial Epithelial Cells by Positive and Negative Regulation of Growth-associated Genes
J. Biol. Chem., August 9, 2002; 277(33): 29999 - 30009.
[Abstract] [Full Text] [PDF]

Home page
 CarcinogenesisHome page
M. Hellmuth, C. Wetzler, M. Nold, J.-H. Chang, S. Frank, J. Pfeilschifter, and H. Muhl
Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate
Carcinogenesis, August 1, 2002; 23(8): 1273 - 1279.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Surg. Oncol.Home page
Y. Shirota, W. Ichikawa, H. Uetake, H. Yamada, Z. Nihei, and K. Sugihara
Intratumoral Dihydropyrimidine Dehydrogenase Messenger RNA Level Reflects Tumor Progression in Human Colorectal Cancer
Ann. Surg. Oncol., July 1, 2002; 9(6): 599 - 603.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
K.-C. Choi, S. K. Kang, C.-J. Tai, N. Auersperg, and P. C. K. Leung
Follicle-Stimulating Hormone Activates Mitogen-Activated Protein Kinase in Preneoplastic and Neoplastic Ovarian Surface Epithelial Cells
J. Clin. Endocrinol. Metab., May 1, 2002; 87(5): 2245 - 2253.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
R. Tamai, T. Sakuta, K. Matsushita, M. Torii, O. Takeuchi, S. Akira, S. Akashi, T. Espevik, S. Sugawara, and H. Takada
Human Gingival CD14+ Fibroblasts Primed with Gamma Interferon Increase Production of Interleukin-8 in Response to Lipopolysaccharide through Up-Regulation of Membrane CD14 and MyD88 mRNA Expression
Infect. Immun., March 1, 2002; 70(3): 1272 - 1278.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
H. Naggar, M. S. Ola, P. Moore, W. Huang, C. C. Bridges, V. Ganapathy, and S. B. Smith
Downregulation of Reduced-Folate Transporter by Glucose in Cultured RPE Cells and in RPE of Diabetic Mice
Invest. Ophthalmol. Vis. Sci., February 1, 2002; 43(2): 556 - 563.
[Abstract] [Full Text] [PDF]

Home page
 Cell Growth Differ.Home page
C. Li, Y. Wang, L. Gao, J. Zhang, J. Shao, S. Wang, W. Feng, X. Wang, M. Li, and Z. Chang
Expression of Toll-like Receptors 2 and 4 and CD14 during Differentiation of HL-60 Cells Induced by Phorbol 12-Myristate 13-Acetate and 1{alpha}, 25-Dihydroxy-Vitamin D3
Cell Growth Differ., January 1, 2002; 13(1): 27 - 38.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
C. C. Bridges, M. S. Ola, P. D. Prasad, A. El-Sherbeny, V. Ganapathy, and S. B. Smith
Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells
Am J Physiol Cell Physiol, December 1, 2001; 281(6): C1825 - C1836.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
V. A. Efimov, O. G. Chakhmakhcheva, J. Archdeacon, J. M. Fernandez, O. N. Fedorkin, Yu. L. Dorokhov, and J. G. Atabekov
Detection of the 5'-cap structure of messenger RNAs with the use of the cap-jumping approach
Nucleic Acids Res., November 15, 2001; 29(22): 4751 - 4759.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
S. Tang, T. Murakami, B. E. Agresta, S. Campbell, E. O. Freed, and J. G. Levin
Human Immunodeficiency Virus Type 1 N-Terminal Capsid Mutants That Exhibit Aberrant Core Morphology and Are Blocked in Initiation of Reverse Transcription in Infected Cells
J. Virol., October 1, 2001; 75(19): 9357 - 9366.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
M. G. Brocardo, R. Schillaci, A. Galeano, M. Radrizzani, V. White, A. G. Guerrico, T. A. Santa-Coloma, and A. Roldan
Early effects of insulin-like growth factor-1 in activated human T lymphocytes
J. Leukoc. Biol., August 1, 2001; 70(2): 297 - 305.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
S. K. Diah, P. K. Smitherman, J. Aldridge, E. L. Volk, E. Schneider, A. J. Townsend, and C. S. Morrow
Resistance to Mitoxantrone in Multidrug-resistant MCF7 Breast Cancer Cells: Evaluation of Mitoxantrone Transport and the Role of Multidrug Resistance Protein Family Proteins
Cancer Res., July 1, 2001; 61(14): 5461 - 5467.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
M. Piva, G. M. Horowitz, and K. L. Sharpe-Timms
Interleukin-6 Differentially Stimulates Haptoglobin Production by Peritoneal and Endometriotic Cells in Vitro: A Model for Endometrial-Peritoneal Interaction in Endometriosis
J. Clin. Endocrinol. Metab., June 1, 2001; 86(6): 2553 - 2561.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
K.-C. Choi, S. K. Kang, C.-J. Tai, N. Auersperg, and P. C. K. Leung
Estradiol Up-Regulates Antiapoptotic Bcl-2 Messenger Ribonucleic Acid and Protein in Tumorigenic Ovarian Surface Epithelium Cells
Endocrinology, June 1, 2001; 142(6): 2351 - 2360.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
K. Ohta, T. Endo, K. Haraguchi, J. M. Hershman, and T. Onaya
Ligands for Peroxisome Proliferator-Activated Receptor {{gamma}} Inhibit Growth and Induce Apoptosis of Human Papillary Thyroid Carcinoma Cells
J. Clin. Endocrinol. Metab., May 1, 2001; 86(5): 2170 - 2177.
[Abstract] [Full Text]

Home page
 Infect. Immun.Home page
S. Yang, R. Tamai, S. Akashi, O. Takeuchi, S. Akira, S. Sugawara, and H. Takada
Synergistic Effect of Muramyldipeptide with Lipopolysaccharide or Lipoteichoic Acid To Induce Inflammatory Cytokines in Human Monocytic Cells in Culture
Infect. Immun., April 1, 2001; 69(4): 2045 - 2053.
[Abstract] [Full Text] [PDF]

Home page
 J Med MicrobiolHome page
T. SAKUTA, K. MATSUSHITA, N. YAMAGUCHI, T. OYAMA, R. MOTANI, T. KOGA, S. NAGAOKA, K. ABEYAMA, I. MARUYAMA, H. TAKADA, et al.
Enhanced production of vascular endothelial growth factor by human monocytic cells stimulated with endotoxin through transcription factor SP-1
J. Med. Microbiol., March 1, 2001; 50(3): 233 - 237.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
C. C. Bridges, R. Kekuda, H. Wang, P. D. Prasad, P. Mehta, W. Huang, S. B. Smith, and V. Ganapathy
Structure, Function, and Regulation of Human Cystine/Glutamate Transporter in Retinal Pigment Epithelial Cells
Invest. Ophthalmol. Vis. Sci., January 1, 2001; 42(1): 47 - 54.
[Abstract] [Full Text]

Home page
 Clin. Cancer Res.Home page
T. Nishiyama, M. Tachibana, Y. Horiguchi, K. Nakamura, Y. Ikeda, K. Takesako, and M. Murai
Immunotherapy of Bladder Cancer Using Autologous Dendritic Cells Pulsed with Human Lymphocyte Antigen-A24-specific MAGE-3 Peptide
Clin. Cancer Res., January 1, 2001; 7(1): 23 - 31.
[Abstract] [Full Text]

Home page
 Am. J. Pathol.Home page
G. Egidy, L. Juillerat-Jeanneret, J.-F. Jeannin, P. Korth, F. T. Bosman, and F. Pinet
Modulation of Human Colon Tumor-Stromal Interactions by the Endothelin System
Am. J. Pathol., December 1, 2000; 157(6): 1863 - 1874.
[Abstract] [Full Text] [PDF]

Home page
 Int ImmunolHome page
M. Kato, T. K. Neil, D. B. Fearnley, A. D. McLellan, S. Vuckovic, and D. N. J. Hart
Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells
Int. Immunol., November 1, 2000; 12(11): 1511 - 1519.
[Abstract] [Full Text] [PDF]

Home page
 Reproductive SciencesHome page
K. E. Cox, K. L. Sharpe-Timms, N. Kamiya, M. Saraf, K. M. Donnelly, and A. T. Fazleabas
Differential Regulation of Stromelysin-1 (Matrix Metalloproteinase-3) and Matrilysin (Matrix Metalloproteinase-7) in Baboon Endometrium
Reproductive Sciences, July 1, 2000; 7(4): 242 - 248.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
S. T. Sinkkonen, M. C. Hanna, E. F. Kirkness, and E. R. Korpi
GABAA Receptor epsilon and theta Subunits Display Unusual Structural Variation between Species and Are Enriched in the Rat Locus Ceruleus
J. Neurosci., May 15, 2000; 20(10): 3588 - 3595.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
Y.-T. Shiu, M. M. Udden, and L. V. McIntire
Perfusion with sickle erythrocytes up-regulates ICAM-1 and VCAM-1 gene expression in cultured human endothelial cells
Blood, May 15, 2000; 95(10): 3232 - 3241.
[Abstract] [Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
S.-K. Park, W. S. Yang, S. K. Lee, H. Ahn, J. S. Park, O. Hwang, and J. D. Lee
TGF-{beta}1 down-regulates inflammatory cytokine-induced VCAM-1 expression in cultured human glomerular endothelial cells
Nephrol. Dial. Transplant., May 1, 2000; 15(5): 596 - 604.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
S. E. Jones, C. Jomary, J. Grist, H. J. Stewart, and M. J. Neal
Altered Expression of Secreted Frizzled-Related Protein-2 in Retinitis Pigmentosa Retinas
Invest. Ophthalmol. Vis. Sci., May 1, 2000; 41(6): 1297 - 1301.
[Abstract] [Full Text]

Home page
 J. Clin. Endocrinol. Metab.Home page
C.-J. Tai, S. K. Kang, K. W. Cheng, K.-C. Choi, P. S. Nathwani, and P. C. K. Leung
Expression and Regulation of P2U-Purinergic Receptor in Human Granulosa-Luteal Cells
J. Clin. Endocrinol. Metab., April 1, 2000; 85(4): 1591 - 1597.
[Abstract] [Full Text]

Home page
 HypertensionHome page
L. S. Sjogren, R. Doroudi, L.-m. Gan, L. Jungersten, T. Hrafnkelsdottir, and S. Jern
Elevated Intraluminal Pressure Inhibits Vascular Tissue Plasminogen Activator Secretion and Downregulates Its Gene Expression
Hypertension, April 1, 2000; 35(4): 1002 - 1008.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
P. Jaquet, A. Saveanu, G. Gunz, F. Fina, A. J. Zamora, M. Grino, M. D. Culler, J. P. Moreau, A. Enjalbert, and L'H. Ouafik
Human Somatostatin Receptor Subtypes in Acromegaly: Distinct Patterns of Messenger Ribonucleic Acid Expression and Hormone Suppression Identify Different Tumoral Phenotypes
J. Clin. Endocrinol. Metab., February 1, 2000; 85(2): 781 - 792.
[Abstract] [Full Text]

Home page
 EndocrinologyHome page
K. J. Greenland, I. Jantke, S. Jenatschke, K. E. Bracken, C. Vinson, and B. Gellersen
The Human NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Gene Promoter Is Controlled by Ets and Activating Protein-1 Transcription Factors and Progesterone
Endocrinology, February 1, 2000; 141(2): 581 - 597.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
S. Dieterich, U. Bieligk, K. Beulich, G. Hasenfuss, and J. Prestle
Gene Expression of Antioxidative Enzymes in the Human Heart : Increased Expression of Catalase in the End-Stage Failing Heart
Circulation, January 4, 2000; 101(1): 33 - 39.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
P. J. Richards, N. Amos, A. S. Williams, and B. D. Williams
Pro-inflammatory effects of the aminobisphosphonate ibandronate in vitro and in vivo
Rheumatology, October 1, 1999; 38(10): 984 - 991.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
P. Jaquet, L. Ouafik, A. Saveanu, G. Gunz, F. Fina, H. Dufour, M. D. Culler, J. P. Moreau, and A. Enjalbert
Quantitative and Functional Expression of Somatostatin Receptor Subtypes in Human Prolactinomas
J. Clin. Endocrinol. Metab., September 1, 1999; 84(9): 3268 - 3276.
[Abstract] [Full Text]