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Comments on Occupational and Environmental Factors in the Origin of Non-Hodgkin's Lymphoma¹

Environmental Epidemiology Branch, National Cancer Institute, NIH, Rockville, Maryland 20892 [A. B., P. A. S., K. P. C.]; Department of Epidemiology, University of Athens, Athens, Greece [A. L.]; Department of Preventive Medicine, University of Iowa, Iowa City, Iowa 52242 [L. F. B.]; Department of Epidemiology, University of Minnesota, Minneapolis, Minnesota 55455 [R. G., L. S.]; and Department of Internal Medicine, Orlando Regional Medical Center, Orlando, Florida 32806 [G. E.]

The review of the literature regarding non-Hodgkin's lymphoma and occupational and environmental factors presented at this workshop suggested associations with viruses, solvents, and hair dyes. A population-based case-control study among men from Iowa and Minnesota notes similar associations. Workers engaged in metal working, hair care, painting, and dry cleaning experienced nonsignificant excesses. Risks from specific exposures showed some variation by histological type. Both follicular and diffuse non-Hodgkin's lymphoma were associated with benzene. The diffuse type was linked to solvents other than benzene and formaldehyde, while the follicular was excessive among workers exposed to oils and greases.